A new method to study the uptake of oxygen from the lungs is demonstrated. The method uses the short lived positron emitting isotope, oxygen-15. Four formulations were studied in four rats each: liposome encapsulated bovine hemoglobin (LEBH), liposome encapsulated human hemolysate (LEHH), free bovine hemoglobin (HEM), and a control saline solution (SAL). The studies demonstrate the feasibility of using this method to assess the oxygen carrying capacity of various blood substitutes.
|Original language||English (US)|
|Journal||Artificial Cells, Blood Substitutes, and Immobilization Biotechnology|
|State||Published - Nov 1 1994|
|Event||Proceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA|
Duration: Jul 24 1994 → Jul 27 1994
ASJC Scopus subject areas
- Biomedical Engineering