Abstract
Purpose: Cryoablation is gaining acceptance as a primary treatment of localized metastatic urologie malignancies as well as a salvage therapy. Anecdotal clinical reports suggest that cryoablation can induce a systemic antitumor immune response, which has been confirmed in animal models also. Materials and Methods: A review of the relevant literature was performed to suggest urologie applications of cryo-immunology. Results: This article reviews the existing evidence regarding cryo-immunology and discusses the mechanisms for generation of an anti-tumor immune response. Conclusions: Our findings suggest combining cryoablation with other immunotherapeutic approaches to devise a cryo-immunotherapeutic strategy with potential to impact the progression of metastatic disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 629-634 |
| Number of pages | 6 |
| Journal | Korean Journal of Urology |
| Volume | 50 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2009 |
| Externally published | Yes |
Keywords
- Cryosurgery
- Immunotherapy
- Kidney neoplasms
- Prostatic neoplasms
ASJC Scopus subject areas
- Urology