Urologic applications of cryo-immunology

Abhinav Sidana, Ronald Rodriguez

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Purpose: Cryoablation is gaining acceptance as a primary treatment of localized metastatic urologie malignancies as well as a salvage therapy. Anecdotal clinical reports suggest that cryoablation can induce a systemic antitumor immune response, which has been confirmed in animal models also. Materials and Methods: A review of the relevant literature was performed to suggest urologie applications of cryo-immunology. Results: This article reviews the existing evidence regarding cryo-immunology and discusses the mechanisms for generation of an anti-tumor immune response. Conclusions: Our findings suggest combining cryoablation with other immunotherapeutic approaches to devise a cryo-immunotherapeutic strategy with potential to impact the progression of metastatic disease.

Original languageEnglish (US)
Pages (from-to)629-634
Number of pages6
JournalKorean Journal of Urology
Volume50
Issue number7
DOIs
StatePublished - Jul 1 2009
Externally publishedYes

Keywords

  • Cryosurgery
  • Immunotherapy
  • Kidney neoplasms
  • Prostatic neoplasms

ASJC Scopus subject areas

  • Urology

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