An increase of 100% in urinary 5-hydroxyindoleacetic acid, as a measure of release and catabolism of serotonin, is associated with the stress of 18 hr of restraint. Seventy percent of the rats developed gastric ulcers. Increased urinary 5-hydroxyindoleacetic acid levels were not observed in rats deprived of food for 42 hr.
- 5-Hydroxyindoleacetic acid (5-HIAA)
- Immobilization stress
- Restraint ulcer
- Serotonin (5-HT)
ASJC Scopus subject areas
- Experimental and Cognitive Psychology
- Behavioral Neuroscience