Unique collision of Hodgkin lymphoma and adenosquamous carcinoma in the uterine cervix: Synchronous malignant neoplasms of the cervix

Michael O. Lovell, Philip T. Valente

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

To document the first reported synchronous occurrence of Hodgkin lymphoma and adenosquamous carcinoma involving the female genital tract. Review of cytologic, histologic, and immunohistochemical studies obtained from a 50-year-old, multiparous, postmenopausal, Hispanic female who had a left inguinal mass, bilateral lower extremity pain and numbness, fatigue, anorexia, a 20- to 30-pound weight loss, and a malodorous vaginal discharge at presentation is presented. Cervical squamous cell carcinoma was diagnosed by routine cytologic and histologic analysis. Hodgkin lymphoma subsequently was diagnosed in the inguinal lymph nodes by fine-needle aspiration biopsy and excisional biopsy before the patient underwent hysterectomy. In addition to invasive and in situ adenosquamous carcinoma of the uterine cervix, the hysterectomy specimen also contained previously unsuspected Hodgkin lymphoma. To our knowledge, this is the first reported case of adenosquamous carcinoma and Hodgkin lymphoma synchronously involving the female reproductive tract.

Original languageEnglish (US)
Pages (from-to)307-310
Number of pages4
JournalJournal of Lower Genital Tract Disease
Volume7
Issue number4
DOIs
StatePublished - Oct 1 2003

Keywords

  • Adenosquamous carcinoma
  • Hodgkin lymphoma
  • Uterus

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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