TY - JOUR
T1 - Under-utilization of implantable cardioverter defibrillators in patients with heart failure - The current state of sudden cardiac death prophylaxis
AU - Pillarisetti, Jayasree
AU - Emert, Martin
AU - Biria, Mazda
AU - Chotia, Rashaad
AU - Guda, Rajeshwer
AU - Bommana, Sudharani
AU - Pimentel, Rhea
AU - Vacek, James
AU - Dendi, Raghuveer
AU - Berenbom, Loren
AU - Dawn, Buddhadeb
AU - Lakkireddy, Dhanunjaya
N1 - Publisher Copyright:
© 2015, Indian Pacing and Electrophysiology Group. All rights reserved.
PY - 2015
Y1 - 2015
N2 - Background: Despite ACC/AHA guidelines indicating implantable cardioverter defibrillator (ICD) as class I therapy for primary prevention of sudden cardiac death in patients with EF≤35%, ICD utilization rates in real world practice have been low. Objective: To determine the rate of ICD implantation at a tertiary care academic center and to assess the reasons for under-utilization of the same. Methods: Review of a prospectively collected database which included all patients diagnosed with an EF≤35% was performed to assess the rate of ICD implantation and mortality. Reasons for non-implantation of ICD were then assessed from detailed chart review. Results: A total of 707 patients (age 69.4 ± 14.1 years) with mean EF of 26±7% were analyzed. Only 28% (200/707) of patients had ICDs implanted. Mortality was lower in the group with ICD (25% vs 37%, p=0.004). When patients who either died or were lost to follow-up prior to 2005 were excluded, ICD utilization rate was still low at 37.6%. The most common reason for non-implantation of ICD was physicians not discussing this option with their patients. Patient refusal was the second most common reason. Conclusions: ICD Implantation rates for primary prevention of SCD in patients with EF≤35% is low. Physician and patient education should be addressed to improve the utilization rates.
AB - Background: Despite ACC/AHA guidelines indicating implantable cardioverter defibrillator (ICD) as class I therapy for primary prevention of sudden cardiac death in patients with EF≤35%, ICD utilization rates in real world practice have been low. Objective: To determine the rate of ICD implantation at a tertiary care academic center and to assess the reasons for under-utilization of the same. Methods: Review of a prospectively collected database which included all patients diagnosed with an EF≤35% was performed to assess the rate of ICD implantation and mortality. Reasons for non-implantation of ICD were then assessed from detailed chart review. Results: A total of 707 patients (age 69.4 ± 14.1 years) with mean EF of 26±7% were analyzed. Only 28% (200/707) of patients had ICDs implanted. Mortality was lower in the group with ICD (25% vs 37%, p=0.004). When patients who either died or were lost to follow-up prior to 2005 were excluded, ICD utilization rate was still low at 37.6%. The most common reason for non-implantation of ICD was physicians not discussing this option with their patients. Patient refusal was the second most common reason. Conclusions: ICD Implantation rates for primary prevention of SCD in patients with EF≤35% is low. Physician and patient education should be addressed to improve the utilization rates.
KW - Implantable cardioverter-defibrillator
KW - Outcomes
KW - Sudden cardiac death
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U2 - 10.1016/S0972-6292(16)30838-5
DO - 10.1016/S0972-6292(16)30838-5
M3 - Article
AN - SCOPUS:84926434678
SN - 0972-6292
VL - 15
SP - 20
EP - 29
JO - Indian Pacing and Electrophysiology Journal
JF - Indian Pacing and Electrophysiology Journal
IS - 1
ER -