Ultrasound-based criteria for adequate peripheral venous access in therapeutic apheresis procedures

Eric Salazar, Faaria Gowani, Francisco Segura, Heather Passe, Lamesha Seamster, Bettie Chapman, Felicia Joubert, Stephanie Hopson, Tracy Easley, Salvador Garcia, Robin Miguel, Cindia Medina, Amer Musharbash, Brian Castillo, Jian Chen, Tina Ipe, Christopher Leveque

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Background: Apheresis procedures require adequate vascular access to achieve adequate inlet flow rates. Central dialysis-type catheters are often used in apheresis, despite their multiple risks. Peripheral venous access is a safe and effective option for many patients. Aim: We previously demonstrated that ultrasound guidance reduces central venous catheter use in apheresis patients; however, no validated criteria for preprocedural evaluation of peripheral veins exist. Here, we hypothesized that ultrasound-based criteria could predict the adequacy of a peripheral vein for apheresis procedures. Patients/Methods: In this pilot cohort study, we reviewed the procedural outcomes for 50 cases of peripheral venous procedures that used our ultrasound-based criteria. Results: Of the procedures that met our criteria, 96% (46/48) were successfully completed. Overall, our criteria had 100% sensitivity, 50% specificity, 96% positive predictive value, and 100% negative predictive value. Conclusion: Our criteria justify an evidence-based ultrasound-guided standard for evaluation of peripheral venous access for apheresis procedures.

Original languageEnglish (US)
Pages (from-to)797-801
Number of pages5
JournalJournal of Clinical Apheresis
Issue number6
StatePublished - Dec 2021
Externally publishedYes


  • apheresis
  • ultrasound
  • venous access

ASJC Scopus subject areas

  • Hematology


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