@article{1f483fbb3e4a4fb8ab6c7c020b3e4374,
title = "Two-Stage Osseointegrated Reconstruction of Post-traumatic Unilateral Transfemoral Amputees",
abstract = "A new technique called osseointegration was introduced recently by intimately connecting the artificial limb prosthesis to the residual bone, eliminating the problematic socket-residuum interface. The objective here is to describe the two-stage strategy for the osseointegrated reconstruction of amputated limbs and discuss the clinical outcomes of the procedure. This is a prospective case series of 37 post-traumatic unilateral transfemoral amputees with a minimum 2-yr follow-up. Outcome measures included the Questionnaire for persons with a Transfemoral Amputation (Q-TFA), the Short Form Health Survey 36 (SF-36), the 6 Minute Walk Test (6MWT), and Timed Up and Go (TUG) tests. Adverse events including infection, revision surgery, fractures, and implant failures were reported. Clinical outcomes for all outcome measures were significantly improved at follow-up. Twelve participants were wheelchair bound pre-operatively; however, all 12 were able to ambulate after osseointegrated reconstruction. Sixteen patients experienced infection episodes but were managed successfully without the need for implant removal. One periprosthetic fracture occurred due to increased activity, which was revised successfully. These results confirm that the procedure is a suitable alternative for post-traumatic unilateral transfemoral amputees experiencing socket-related discomfort, with the potential to reduce recovery time compared with other treatment protocols.",
keywords = "Reconstructive surgery, amputation, osseointegration, prosthetics, rehabilitation",
author = "Muderis, {Munjed Al} and William Lu and Vaida Glatt and Kevin Tetsworth",
note = "Funding Information: *The Australian School of Advanced Medicine, Macquarie University Hospital, Macquarie University, Suite 303 Level 3, 2 Technology Place, NSW 2109, Australia. †School of Medicine, The University of Notre Dame Australia, 160 Oxford Street, Darlinghurst, Sydney, NSW 2010, Australia. ‡Norwest Private Hospital, Suite G3, 9 Norbrik Drive, Bella Vista, NSW 2153, Australia. §Clinical Research Department, The Osseointegration Group of Australia, 23A King George Street, McMahons Point, NSW 2060, Australia. ¶National Health and Medical Research Council (NHMRC) Clinical Trials Centre, The University of Sydney, 92-94 Parramatta Rd, Camperdown, NSW 2050, Australia. ††Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, Brisbane, QLD 4059, Australia. ‡‡Royal Brisbane Hospital, Level 7, Ned Hanlon Building Butterfield street, Herston, Brisbane, QLD 4029, Australia. §§Orthopaedic Research Center of Australia, Level 7 Ned Hanlon Building, Butterfield Street, Herston, Brisbane, QLD 4029, Australia. Dr. Al Muderis reports personal fees from Permedica S.p.A (Italy) and AQ Implants GmbH (Germany) during the conduct of the study. Dr. William Lu reports personal fees from Osseointegration International Pty Ltd (Australia) during the conduct of the study. doi: 10.1093/milmed/usx185 {\textcopyright} Association of Military Surgeons of the United States 2018. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. Publisher Copyright: {\textcopyright} Association of Military Surgeons of the United States 2018. All rights reserved.",
year = "2018",
month = mar,
day = "1",
doi = "10.1093/milmed/usx185",
language = "English (US)",
volume = "183",
pages = "496--502",
journal = "Military Medicine",
issn = "0026-4075",
publisher = "Association of Military Surgeons of the US",
}