Two new species of Mucor from clinical samples

Eduardo Lvarez, Josep Cano, Alberto M. Stchigel, Deanna A. Sutton, Annette W. Fothergill, Valentina Salas, Michael G. Rinaldi, Josep Guarro

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Two new species in the order Mucorales, Mucor velutinosus and Mucor ellipsoideus, isolated from human clinical specimens in the USA, are described and illustrated. The former species is similar to Mucor ramosissimus, from which it can be differentiated by its ability to grow at 37°C and produce verrucose sporangiospores. Mucor ellipsoideus is also able to grow and sporulate at 37°C like M. indicus, the nearest phylogenetic species in this study, however, the former has narrow ellipsoidal sporangiospores in contrast to the subglobose to ellipsoidal sporangiospores of M. indicus. Analysis of the sequences of the ITS and the D1D2 regions of the rRNA genes confirmed the novelty of these species. The in vitro antifungal susceptibility of the new species showed that amphotericin B was active against all isolates and posaconazole and itraconazole showed low activity.

Original languageEnglish (US)
Pages (from-to)62-72
Number of pages11
JournalMedical Mycology
Volume49
Issue number1
DOIs
StatePublished - Jan 2010

Fingerprint

Mucor
new species
Mucorales
sampling
Itraconazole
itraconazole
amphotericin B
Amphotericin B
rRNA Genes
Sequence Analysis
sequence analysis
ribosomal RNA
phylogeny
genes

Keywords

  • Mucor
  • Mucorales
  • Mucormycosis
  • Zygomycetes

ASJC Scopus subject areas

  • veterinary(all)
  • Infectious Diseases

Cite this

Lvarez, E., Cano, J., Stchigel, A. M., Sutton, D. A., Fothergill, A. W., Salas, V., ... Guarro, J. (2010). Two new species of Mucor from clinical samples. Medical Mycology, 49(1), 62-72. https://doi.org/10.3109/13693786.2010.499521

Two new species of Mucor from clinical samples. / Lvarez, Eduardo; Cano, Josep; Stchigel, Alberto M.; Sutton, Deanna A.; Fothergill, Annette W.; Salas, Valentina; Rinaldi, Michael G.; Guarro, Josep.

In: Medical Mycology, Vol. 49, No. 1, 01.2010, p. 62-72.

Research output: Contribution to journalArticle

Lvarez, E, Cano, J, Stchigel, AM, Sutton, DA, Fothergill, AW, Salas, V, Rinaldi, MG & Guarro, J 2010, 'Two new species of Mucor from clinical samples', Medical Mycology, vol. 49, no. 1, pp. 62-72. https://doi.org/10.3109/13693786.2010.499521
Lvarez E, Cano J, Stchigel AM, Sutton DA, Fothergill AW, Salas V et al. Two new species of Mucor from clinical samples. Medical Mycology. 2010 Jan;49(1):62-72. https://doi.org/10.3109/13693786.2010.499521
Lvarez, Eduardo ; Cano, Josep ; Stchigel, Alberto M. ; Sutton, Deanna A. ; Fothergill, Annette W. ; Salas, Valentina ; Rinaldi, Michael G. ; Guarro, Josep. / Two new species of Mucor from clinical samples. In: Medical Mycology. 2010 ; Vol. 49, No. 1. pp. 62-72.
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