Tutorial on lipidomics

Jianing Wang; Chunyan Wang; Xianlin Han

doi:10.1016/j.aca.2019.01.043

Tutorial on lipidomics

Jianing Wang, Chunyan Wang, Xianlin Han

Department of Medicine

Research output: Contribution to journal › Review article › peer-review

86 Scopus citations

Abstract

The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some introduction on the topic is needed to help the newcomers to better understand the field. This tutorial seeks to introduce the basic knowledge about lipidomics and to provide readers with some core ideas and the most important approaches for studying the field.

Original language	English (US)
Pages (from-to)	28-41
Number of pages	14
Journal	Analytica Chimica Acta
Volume	1061
DOIs	https://doi.org/10.1016/j.aca.2019.01.043
State	Published - Jul 11 2019

Keywords

Lipidomics
Lipids
Mass spectrometry
Metabolic syndrome
Neurodegenerative diseases
Shotgun lipidomics

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Environmental Chemistry
Spectroscopy

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10.1016/j.aca.2019.01.043

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title = "Tutorial on lipidomics",

abstract = "The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some introduction on the topic is needed to help the newcomers to better understand the field. This tutorial seeks to introduce the basic knowledge about lipidomics and to provide readers with some core ideas and the most important approaches for studying the field.",

keywords = "Lipidomics, Lipids, Mass spectrometry, Metabolic syndrome, Neurodegenerative diseases, Shotgun lipidomics",

author = "Jianing Wang and Chunyan Wang and Xianlin Han",

note = "Funding Information: This work was partially supported by NIGMS ( R01 GM105724 ), NIH/NIA ( RF1 AG061872 ), intramural institutional research funds from the University of Texas Health Science Center at San Antonio ( UT Health SA ), the Mass Spectrometry Core Facility of UT Health SA , and the Methodist Hospital Foundation endowment . Funding Information: This work was partially supported by NIGMS (R01 GM105724), NIH/NIA (RF1 AG061872), intramural institutional research funds from the University of Texas Health Science Center at San Antonio (UT Health SA), the Mass Spectrometry Core Facility of UT Health SA, and the Methodist Hospital Foundation endowment. Publisher Copyright: {\textcopyright} 2019 Elsevier B.V.",

year = "2019",

month = jul,

day = "11",

doi = "10.1016/j.aca.2019.01.043",

language = "English (US)",

volume = "1061",

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journal = "Analytica Chimica Acta",

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AU - Wang, Jianing

AU - Wang, Chunyan

AU - Han, Xianlin

N1 - Funding Information: This work was partially supported by NIGMS ( R01 GM105724 ), NIH/NIA ( RF1 AG061872 ), intramural institutional research funds from the University of Texas Health Science Center at San Antonio ( UT Health SA ), the Mass Spectrometry Core Facility of UT Health SA , and the Methodist Hospital Foundation endowment . Funding Information: This work was partially supported by NIGMS (R01 GM105724), NIH/NIA (RF1 AG061872), intramural institutional research funds from the University of Texas Health Science Center at San Antonio (UT Health SA), the Mass Spectrometry Core Facility of UT Health SA, and the Methodist Hospital Foundation endowment. Publisher Copyright: © 2019 Elsevier B.V.

PY - 2019/7/11

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N2 - The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some introduction on the topic is needed to help the newcomers to better understand the field. This tutorial seeks to introduce the basic knowledge about lipidomics and to provide readers with some core ideas and the most important approaches for studying the field.

AB - The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some introduction on the topic is needed to help the newcomers to better understand the field. This tutorial seeks to introduce the basic knowledge about lipidomics and to provide readers with some core ideas and the most important approaches for studying the field.

KW - Lipidomics

KW - Lipids

KW - Mass spectrometry

KW - Metabolic syndrome

KW - Neurodegenerative diseases

KW - Shotgun lipidomics

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M3 - Review article

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SP - 28

EP - 41

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

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Tutorial on lipidomics

Abstract

Keywords

ASJC Scopus subject areas

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