Tuberculosis (Mycobacterium tuberculosis) in a pregnant baboon (Papio cynocephalus)

M. Martino, G. B. Hubbard, Natalie Schlabritz-loutsevitch

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Background: Old World monkeys are considered more susceptible to tuberculosis (TB) than New World monkeys. Several cases of TB in baboons are described in the literature. The data regarding baboon reaction to the tuberculin skin test (TST) are controversial. Some authors described anergy in this species, while the others documented a positive reaction. Case Report: An 8-year-old clinically healthy pregnant female baboon (Papio cynocephalus anubis) developed positive TST after 3 years of negative tests in captivity while not pregnant. Thoracic radiographs demonstrated three nodular densities in the lung. Results: Histological examination of tracheobronchial lymph nodes revealed multiple coalescing pyogranulomas filled with caseonecrotic debris and mineralized foci with numerous large foreign body-type and Langhans-type multinucleated giant cells. The bacterial culture contained a slow growing Mycobacterium tuberculosis complex. Conclusions: We describe, to the best of our knowledge, the first case of a positive TST in a wild caught, pregnant baboon with latent infection after 3 years in captivity.

Original languageEnglish (US)
Pages (from-to)108-112
Number of pages5
JournalJournal of medical primatology
Issue number2
StatePublished - Apr 2007
Externally publishedYes


  • Anergy
  • Nonhuman primate
  • Tuberculin reaction

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


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