Tuberculosis biomarker and surrogate endpoint research roadmap

Payam Nahid; Jussi Saukkonen; William R. Mac Kenzie; John L. Johnson; Patrick P.J. Phillips; Janet Andersen; Erin Bliven-Sizemore; John T. Belisle; W. Henry Boom; Annie Luetkemeyer; Thomas B. Campbell; Kathleen D. Eisenach; Richard Hafner; Jeffrey L. Lennox; Mamodikoe Makhene; Susan Swindells; M. Elsa Villarino; Marc Weiner; Constance Benson; William Burman

doi:10.1164/rccm.201105-0827WS

Tuberculosis biomarker and surrogate endpoint research roadmap

Payam Nahid, Jussi Saukkonen, William R. Mac Kenzie, John L. Johnson, Patrick P.J. Phillips, Janet Andersen, Erin Bliven-Sizemore, John T. Belisle, W. Henry Boom, Annie Luetkemeyer, Thomas B. Campbell, Kathleen D. Eisenach, Richard Hafner, Jeffrey L. Lennox, Mamodikoe Makhene, Susan Swindells, M. Elsa Villarino, Marc Weiner, Constance Benson, William Burman

Medicine

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

The Centers for Disease Control and Prevention and National Institutes of Health convened a multidisciplinary meeting to discuss surrogate markers of treatment response in tuberculosis. The goals were to assess recent surrogate marker research and to provide specific recommendations for (1) the qualification and validation of biomarkers of treatment outcome; (2) the standardization of specimen and data collection for future clinical trials, including a minimum set of samples and collection time points; and (3) the creation of a specimen repository to support biomarker testing. This article summarizes these recommendations and provides a roadmap for their implementation.

Original language	English (US)
Pages (from-to)	972-979
Number of pages	8
Journal	American Journal of Respiratory and Critical Care Medicine
Volume	184
Issue number	8
DOIs	https://doi.org/10.1164/rccm.201105-0827WS
State	Published - Oct 15 2011

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

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Nahid, P., Saukkonen, J., Mac Kenzie, W. R., Johnson, J. L., Phillips, P. P. J., Andersen, J., Bliven-Sizemore, E., Belisle, J. T., Boom, W. H., Luetkemeyer, A., Campbell, T. B., Eisenach, K. D., Hafner, R., Lennox, J. L., Makhene, M., Swindells, S., Villarino, M. E., Weiner, M., Benson, C., & Burman, W. (2011). Tuberculosis biomarker and surrogate endpoint research roadmap. American Journal of Respiratory and Critical Care Medicine, 184(8), 972-979. https://doi.org/10.1164/rccm.201105-0827WS

Tuberculosis biomarker and surrogate endpoint research roadmap. / Nahid, Payam; Saukkonen, Jussi; Mac Kenzie, William R.; Johnson, John L.; Phillips, Patrick P.J.; Andersen, Janet; Bliven-Sizemore, Erin; Belisle, John T.; Boom, W. Henry; Luetkemeyer, Annie; Campbell, Thomas B.; Eisenach, Kathleen D.; Hafner, Richard; Lennox, Jeffrey L.; Makhene, Mamodikoe; Swindells, Susan; Villarino, M. Elsa; Weiner, Marc; Benson, Constance; Burman, William.

In: American Journal of Respiratory and Critical Care Medicine, Vol. 184, No. 8, 15.10.2011, p. 972-979.

Research output: Contribution to journal › Article › peer-review

Nahid, P, Saukkonen, J, Mac Kenzie, WR, Johnson, JL, Phillips, PPJ, Andersen, J, Bliven-Sizemore, E, Belisle, JT, Boom, WH, Luetkemeyer, A, Campbell, TB, Eisenach, KD, Hafner, R, Lennox, JL, Makhene, M, Swindells, S, Villarino, ME, Weiner, M, Benson, C & Burman, W 2011, 'Tuberculosis biomarker and surrogate endpoint research roadmap', American Journal of Respiratory and Critical Care Medicine, vol. 184, no. 8, pp. 972-979. https://doi.org/10.1164/rccm.201105-0827WS

Nahid, Payam ; Saukkonen, Jussi ; Mac Kenzie, William R. ; Johnson, John L. ; Phillips, Patrick P.J. ; Andersen, Janet ; Bliven-Sizemore, Erin ; Belisle, John T. ; Boom, W. Henry ; Luetkemeyer, Annie ; Campbell, Thomas B. ; Eisenach, Kathleen D. ; Hafner, Richard ; Lennox, Jeffrey L. ; Makhene, Mamodikoe ; Swindells, Susan ; Villarino, M. Elsa ; Weiner, Marc ; Benson, Constance ; Burman, William. / Tuberculosis biomarker and surrogate endpoint research roadmap. In: American Journal of Respiratory and Critical Care Medicine. 2011 ; Vol. 184, No. 8. pp. 972-979.

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Tuberculosis biomarker and surrogate endpoint research roadmap

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ASJC Scopus subject areas

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