Trichosporonosis Presenting as an Exophytic Cutaneous Mass Lesion

Opportunistic fungal pathogens have increased in frequency with the growing immunosuppressed population. New and emerging pathogens, including the rare yeasts, continue to cause significant morbidity and mortality and frequently develop despite prophylaxis with antifungal agents. We report a previously unreported manifestation of disseminated trichosporonosis. Our patient with underlying acute myeloid leukemia presented with as an exophytic toe lesion found secondary to Trichosporon asahii. We highlight the need for a high index of suspicion to diagnose breakthrough infections and the need for aggressive treatment.