Trichomonas vaginalis: Observation of coexistence of multiple viruses in the same isolate

Marlene Benchimol, T. H. Chang, John F. Alderete

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Trichomonas vaginalis is a flagellated, parasitic protozoan that inhabits the urogenital tract of humans. Some isolates of T. vaginalis are infected with a double-stranded RNA (dsRNA) virus, which was described in the literature as homogeneous icosahedral viral particles with an isometric symmetry and 33 nm in diameter. This study examined in detail the viral particles in T. vaginalis isolate 347 and describes a heterogeneous population of viral particles. The different dsRNA viruses were only observed after a change in the technique. The sample was prepared by the negative staining carbon-film method directly onto freshly cleft mica. The detected viruses ranged in size from 33 to 200 nm. Among the shapes observed were filamentous, cylindrical, and spherical particles. These results show that T. vaginalis may be a reservoir for several different dsRNA viruses simultaneously.

Original languageEnglish (US)
Pages (from-to)197-201
Number of pages5
JournalFEMS Microbiology Letters
Volume215
Issue number2
DOIs
StatePublished - Oct 8 2002
Externally publishedYes

Keywords

  • Negative staining
  • Trichomonas vaginalis
  • Virus

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology
  • Genetics

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