Trex2 responds to damaged replication forks in diverse ways

Research output: Contribution to journalArticlepeer-review

Abstract

Three prime Repair Exonuclease 2 (Trex2) alters replication fork (RF) stability and mutation levels in cells defective for homologous recombination (HR). Trex2 has multiple functions that can either cause or supress RF instability in cells with different HR-defects. Why does Trex2 have such diverse effects on RF maintenance?.

Original languageEnglish (US)
Article number1881394
JournalMolecular and Cellular Oncology
Volume8
Issue number2
DOIs
StatePublished - 2021

ASJC Scopus subject areas

  • Molecular Medicine
  • Cancer Research

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