Treatment of Acutely Ruptured Cerebral Aneurysms with the Woven EndoBridge Device: Experience Post-FDA Approval

Fadi Al Saiegh, David Hasan, Nikolaos Mouchtouris, Mario Zanaty, Ahmad Sweid, Omaditya Khanna, Nohra Chalouhi, Ritam Ghosh, Stavropoula Tjoumakaris, M. Reid Gooch, Robert Rosenwasser, Pascal Jabbour

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

BACKGROUND: Coil embolization of ruptured bifurcation aneurysms is challenging and often necessitates adjunctive stenting, which requires antiplatelet therapy in the setting of subarachnoid hemorrhage (SAH). The Woven EndoBridge (WEB; Terumo) device is an alternative self-expanding 3D mesh that does not require antiplatelet agents. However, its use has been mostly reserved for unruptured aneurysms. OBJECTIVE: To assess the safety and feasibility of ruptured aneurysm treatment with the WEB. METHODS: Retrospective analysis of 9 SAH patients with 11 aneurysms that were treated with the WEB device at 2 institutions after FDA approval. RESULTS: Hunt and Hess grades were III and IV in 4 (44%) each and V in 1 (11%). All patients were treated within 24 h of hospitalization, and a single WEB was used in all but one aneurysm. Aneurysms treated were 3 basilar tip, 2 anterior communicating artery, 2 posterior inferior cerebellarartery, 1 middle cerebral artery, 1 carotid-ophthalmic artery, 1 posterior communicating artery, and 1 vertebrobasilar junction. Mean aneurysm height and width were 6.2 ± 2.2 mm (range: 3-10) and 5.6 ± 3.0 mm (range: 3.3-14), respectively. Mean dome-To-neck ratio was 1.7 ± 0.8 (range: 1.0-3.8). There was one intraoperative rupture that occurred because of device dislodgement and was managed with embolization. There were no treatment-related mortalities and no re-rupture after securement of the aneurysms with the WEB. CONCLUSION: Our preliminary experience indicates that the WEB device can be used safely for ruptured aneurysms of various sizes in the anterior and posterior circulation. Larger series with long-Term follow-up are necessary to confirm our findings.

Original languageEnglish (US)
Pages (from-to)E16-E22
JournalNeurosurgery
Volume87
Issue number1
DOIs
StatePublished - Jul 1 2020
Externally publishedYes

Keywords

  • Cerebral aneurysm
  • Embolization
  • Endovascular
  • Subarachnoid hemorrhage
  • WEB device

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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