Transparenchymal suture fixation and testicular histology in a prepubertal rat model

T. K. Dixon, M. L. Ritchey, W. Boykin, B. Harper, E. Zeidman, I. M. Thompson

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

We evaluate the effect on testicular histology when fine suture materials are used for transparenchymal suture fixation of the testis during orchiopexy in immature Sprague-Dawley rats. Significant inflammatory reactions were observed in all groups of animals with suture fixation regardless of suture size and material. Only 5% of the animals in the dartos pouch control group had an inflammatory response and no inflammation was noted in the nonoperative controls. Although these findings have not been documented in humans, this evidence raises concerns about the impact of surgical technique on the future reproductive capabilities of these testes. Alternatives to transparenchymal suture fixation of the testis should be considered in patients with cryptorchidism and testicular torsion. Sutureless dartos pouch placement may provide adequate fixation during most orchiopexies without risking injury to testicular structure and function.

Original languageEnglish (US)
Pages (from-to)1116-1118
Number of pages3
JournalJournal of Urology
Volume149
Issue number5
DOIs
StatePublished - Jan 1 1993

Keywords

  • histology
  • rats, inbred strains
  • suture techniques
  • testis

ASJC Scopus subject areas

  • Urology

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    Dixon, T. K., Ritchey, M. L., Boykin, W., Harper, B., Zeidman, E., & Thompson, I. M. (1993). Transparenchymal suture fixation and testicular histology in a prepubertal rat model. Journal of Urology, 149(5), 1116-1118. https://doi.org/10.1016/S0022-5347(17)36312-7