Transmission of genital mycoplasmas from mother to neonate in women with prolonged membrane rupture

Mara J. Dinsmoor, Rajam S. Ramamurthy, Ronald S. Gibbs

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Colonization of the neonate with genital mycoplasmas occurs during passage through a colonized birth canal or in utero via contamination of the amniotic fluid. To define further the route of transmission we obtained cultures from the maternal vagina, the amniotic fluid and the neonatal pharynx in 131 mother-baby pairs. Sixty-six percent (33 of 50) of the corresponding amniotic fluids were colonized when the vagina was colonized with Mycoplasma hominis. When the amniotic fluid contained M. hominis, 26% (9 of 34) of the neonates were colonized. Sixty percent (66 of 110) of the corresponding amniotic fluids were colonized when the vagina was colonized with Ureaplasma urealyticum. When the amniotic fluid contained U. urealyticum, 32% (22 of 69) of the neonates were colonized. No neonates were colonized with M. hominis without prior colonization of both the vagina and the amniotic fluid. We conclude that colonization of the amniotic fluid is an important intermediate step in colonization of the neonate with genital mycoplasmas.

Original languageEnglish (US)
Pages (from-to)483-487
Number of pages5
JournalPediatric Infectious Disease Journal
Volume8
Issue number8
DOIs
StatePublished - Aug 1989

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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