TY - JOUR
T1 - Transient appearance of the lupus anticoagulant in three family members sharing the A11B35DR4 haplotype
AU - Bussel, James
AU - Kempin, Sanford
AU - Miller, Scott
AU - Pollack, Marilyn
AU - Hilgartner, Margaret
AU - Miller, Denis
AU - O’Reilly, Richard
PY - 1983
Y1 - 1983
N2 - A prolonged partial thromboplastin time in a patient was investigated, as well as those of his family members. One sibling, the mother, and the patient all shared a lupus-like anticoagulant and low Factor XII levels in association with the A 11, Bw 35, DR 4 haplotype previously found in familial lupus erythematosis. The rest of the family had normal coagulation profiles and the entire family had normal findings when tested for ANA, complement and immune complexes. After being confirmed in a second coagulation laboratory, the lupus-like anticoagulants in the three affected members of the family disappeared upon retesting 3–8 weeks later.
AB - A prolonged partial thromboplastin time in a patient was investigated, as well as those of his family members. One sibling, the mother, and the patient all shared a lupus-like anticoagulant and low Factor XII levels in association with the A 11, Bw 35, DR 4 haplotype previously found in familial lupus erythematosis. The rest of the family had normal coagulation profiles and the entire family had normal findings when tested for ANA, complement and immune complexes. After being confirmed in a second coagulation laboratory, the lupus-like anticoagulants in the three affected members of the family disappeared upon retesting 3–8 weeks later.
UR - http://www.scopus.com/inward/record.url?scp=0021034602&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021034602&partnerID=8YFLogxK
M3 - Article
C2 - 6414325
AN - SCOPUS:0021034602
SN - 1077-4114
VL - 5
SP - 275
EP - 278
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
IS - 3
ER -