Transcription of novel open reading frames of AIDS retrovirus during infection of lymphocytes

Arnold B. Rabson, Daryl F. Daugherty, Sundararajan Venkatesan, Kim E. Boulukos, Steven I. Benn, Thomas M. Folks, Paul Feorino, Malcolm A. Martin

    Research output: Contribution to journalArticle

    36 Scopus citations

    Abstract

    The retrovirus frequently isolated from patients with the acquired immune deficiency syndrome (AIDS) has two novel open reading frames previously designated "A" and "B." The "A" region was found to be specifically expressed as polyadenylated RNA's of 5.5 and 5.0 kilobases in infected cells. The "B" region was expressed as 1.8- to 2.0-kilobase RNA species. Additional full-length and spliced messenger RNA's of the env region were also identified.

    Original languageEnglish (US)
    Pages (from-to)1388-1390
    Number of pages3
    JournalScience
    Volume229
    Issue number4720
    DOIs
    StatePublished - Jan 1 1985

    ASJC Scopus subject areas

    • General

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    Rabson, A. B., Daugherty, D. F., Venkatesan, S., Boulukos, K. E., Benn, S. I., Folks, T. M., Feorino, P., & Martin, M. A. (1985). Transcription of novel open reading frames of AIDS retrovirus during infection of lymphocytes. Science, 229(4720), 1388-1390. https://doi.org/10.1126/science.2994220