Transatlantic progress in measurement of cognitive outcomes in paediatric oncology trials

Sophie Thomas, Leanne Embry, Karin Walsh, Kim Bull, Richard Grundy, Colin Kennedy, Jurgen Lemiere, Pablo Hernáiz Driever, Jennifer Limond, Mathilde Chevignard, Kristina Hardy

Research output: Contribution to journalArticlepeer-review


The importance of measuring quality of survival within paediatric oncology trials is increasingly recognised. However, capturing neuropsychological outcomes and other aspects of quality of survival in the context of large or multinational trials can be challenging. We provide examples of protocols designed to address this challenge recently employed in clinical trials in the USA and Europe. We discuss their respective strengths and challenges, obstacles encountered and future opportunities for transatlantic collaboration.

Original languageEnglish (US)
JournalPediatric Blood and Cancer
StateAccepted/In press - 2023


  • brain tumour
  • cancer
  • child
  • cognitive
  • late effects
  • paediatric
  • quality of survival

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


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