Toxoplasmosis presenting as panhypopituitarism in a patient with the acquired immune deficiency syndrome

Shawn A. Milligan, Michael S. Katz, Philip C. Craven, Donald A. Strandberg, I. Jon Russell, Richard A. Becker

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

A 57-year-old man with a prior episode of lymphatic toxoplasmosis presented with signs of anterior panhypopituitarism, which was confirmed by standard endocrinologic evaluation. The diagnosis of central nervous system toxoplasmosis was established by brain biopsy after nondlagnostic serologic and radiographic studies. At autopsy, the anterior pituitary was necrotic, with Toxoplasma abscesses in neighboring brain structures. Clinical and laboratory data met the criteria for the acquired immune deficiency syndrome. Although this is the first reported case of toxoplasmosis presenting as panhypopituitarism, future cases may be identified since central nervous system toxoplasmosis is being recognized more frequently in patients with immunodeficiency.

Original languageEnglish (US)
Pages (from-to)760-764
Number of pages5
JournalThe American Journal of Medicine
Volume77
Issue number4
DOIs
StatePublished - Oct 1984

ASJC Scopus subject areas

  • Medicine(all)

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