Toward individual glomerular phenotyping: advent of precision medicine in kidney biopsies

Kumar Sharma; Ljiljana Paša-Tolić

doi:10.1016/j.kint.2018.01.035

Toward individual glomerular phenotyping: advent of precision medicine in kidney biopsies

Kumar Sharma
, Ljiljana Paša-Tolić

Research output: Contribution to journal › Comment/debate › peer-review

2 Scopus citations

Abstract

The road to precision medicine for nephrology is approaching quickly. In the present volume, the glomerular proteome has now been characterized at a single glomerulus level in mouse and human kidneys. Using the Single-Pot Solid-Phase–enhanced Sample Preparation (SP3) approach the authors demonstrated that LAMP1 is a key lysosomal protein that is increased in glomerular diseases and may play a pathogenic role.

Original language	English (US)
Pages (from-to)	1265-1267
Number of pages	3
Journal	Kidney international
Volume	93
Issue number	6
DOIs	https://doi.org/10.1016/j.kint.2018.01.035
State	Published - Jun 2018

ASJC Scopus subject areas

Nephrology

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10.1016/j.kint.2018.01.035

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title = "Toward individual glomerular phenotyping: advent of precision medicine in kidney biopsies",

abstract = "The road to precision medicine for nephrology is approaching quickly. In the present volume, the glomerular proteome has now been characterized at a single glomerulus level in mouse and human kidneys. Using the Single-Pot Solid-Phase–enhanced Sample Preparation (SP3) approach the authors demonstrated that LAMP1 is a key lysosomal protein that is increased in glomerular diseases and may play a pathogenic role.",

author = "Kumar Sharma and Ljiljana Pa{\v s}a-Toli{\'c}",

note = "Publisher Copyright: {\textcopyright} 2018 International Society of Nephrology",

year = "2018",

month = jun,

doi = "10.1016/j.kint.2018.01.035",

language = "English (US)",

volume = "93",

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journal = "Kidney international",

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T1 - Toward individual glomerular phenotyping

T2 - advent of precision medicine in kidney biopsies

AU - Sharma, Kumar

AU - Paša-Tolić, Ljiljana

PY - 2018/6

Y1 - 2018/6

N2 - The road to precision medicine for nephrology is approaching quickly. In the present volume, the glomerular proteome has now been characterized at a single glomerulus level in mouse and human kidneys. Using the Single-Pot Solid-Phase–enhanced Sample Preparation (SP3) approach the authors demonstrated that LAMP1 is a key lysosomal protein that is increased in glomerular diseases and may play a pathogenic role.

AB - The road to precision medicine for nephrology is approaching quickly. In the present volume, the glomerular proteome has now been characterized at a single glomerulus level in mouse and human kidneys. Using the Single-Pot Solid-Phase–enhanced Sample Preparation (SP3) approach the authors demonstrated that LAMP1 is a key lysosomal protein that is increased in glomerular diseases and may play a pathogenic role.

UR - https://www.scopus.com/pages/publications/85047003572

UR - https://www.scopus.com/pages/publications/85047003572#tab=citedBy

U2 - 10.1016/j.kint.2018.01.035

DO - 10.1016/j.kint.2018.01.035

M3 - Comment/debate

C2 - 29792268

AN - SCOPUS:85047003572

SN - 0085-2538

VL - 93

SP - 1265

EP - 1267

JO - Kidney international

JF - Kidney international

IS - 6

ER -

Toward individual glomerular phenotyping: advent of precision medicine in kidney biopsies

Abstract

ASJC Scopus subject areas

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