Toward individual glomerular phenotyping: advent of precision medicine in kidney biopsies

Kumar Sharma, Ljiljana Paša-Tolić

Research output: Contribution to journalComment/debatepeer-review

Abstract

The road to precision medicine for nephrology is approaching quickly. In the present volume, the glomerular proteome has now been characterized at a single glomerulus level in mouse and human kidneys. Using the Single-Pot Solid-Phase–enhanced Sample Preparation (SP3) approach the authors demonstrated that LAMP1 is a key lysosomal protein that is increased in glomerular diseases and may play a pathogenic role.

Original languageEnglish (US)
Pages (from-to)1265-1267
Number of pages3
JournalKidney international
Volume93
Issue number6
DOIs
StatePublished - Jun 2018

ASJC Scopus subject areas

  • Nephrology

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