Toward a human epigenome

Romulo M. Brena; Tim H.M. Huang; Christoph Plass

doi:10.1038/ng1206-1359

Toward a human epigenome

Romulo M. Brena
, Tim H.M. Huang
, Christoph Plass

Research output: Contribution to journal › Short survey › peer-review

58 Scopus citations

Abstract

Sequencing of genomes, including that of humans, has revolutionized our understanding of genome organization and accelerated the hunt for disease-causing mutations. New studies by the Human Epigenome Project (HEP) now highlight the importance and complexity of cytosine DNA methylation in tissue-specific regulation of gene expression.

Original language	English (US)
Pages (from-to)	1359-1360
Number of pages	2
Journal	Nature Genetics
Volume	38
Issue number	12
DOIs	https://doi.org/10.1038/ng1206-1359
State	Published - Dec 5 2006
Externally published	Yes

ASJC Scopus subject areas

Genetics

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10.1038/ng1206-1359

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title = "Toward a human epigenome",

abstract = "Sequencing of genomes, including that of humans, has revolutionized our understanding of genome organization and accelerated the hunt for disease-causing mutations. New studies by the Human Epigenome Project (HEP) now highlight the importance and complexity of cytosine DNA methylation in tissue-specific regulation of gene expression.",

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T1 - Toward a human epigenome

AU - Brena, Romulo M.

AU - Huang, Tim H.M.

AU - Plass, Christoph

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N2 - Sequencing of genomes, including that of humans, has revolutionized our understanding of genome organization and accelerated the hunt for disease-causing mutations. New studies by the Human Epigenome Project (HEP) now highlight the importance and complexity of cytosine DNA methylation in tissue-specific regulation of gene expression.

AB - Sequencing of genomes, including that of humans, has revolutionized our understanding of genome organization and accelerated the hunt for disease-causing mutations. New studies by the Human Epigenome Project (HEP) now highlight the importance and complexity of cytosine DNA methylation in tissue-specific regulation of gene expression.

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UR - https://www.scopus.com/pages/publications/33751521034#tab=citedBy

U2 - 10.1038/ng1206-1359

DO - 10.1038/ng1206-1359

M3 - Short survey

C2 - 17133218

AN - SCOPUS:33751521034

SN - 1061-4036

VL - 38

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EP - 1360

JO - Nature Genetics

JF - Nature Genetics

IS - 12

ER -

Toward a human epigenome

Abstract

ASJC Scopus subject areas

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