Toward a human epigenome

Romulo M. Brena, Tim H.M. Huang, Christoph Plass

Research output: Contribution to journalShort survey

48 Scopus citations

Abstract

Sequencing of genomes, including that of humans, has revolutionized our understanding of genome organization and accelerated the hunt for disease-causing mutations. New studies by the Human Epigenome Project (HEP) now highlight the importance and complexity of cytosine DNA methylation in tissue-specific regulation of gene expression.

Original languageEnglish (US)
Pages (from-to)1359-1360
Number of pages2
JournalNature Genetics
Volume38
Issue number12
DOIs
StatePublished - Dec 5 2006
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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