Topiramate-induced palinopsia: A case series and review of the literature

Samuel H. Yun, Patrick J. Lavin, Martha P. Schatz, Robert L. Lesser

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Background: To report palinopsia as a possible side effect of topiramate. Methods: Case series and review of the literature. Results: Nine patients in our series, and 4 previously reported patients, who developed palinopsia while on topiramate, are reviewed. All patients were women, and comorbidities included migraine, idiopathic intracranial hypertension, and bulimia nervosa. Palinopsia resolved in 8 patients after stopping or decreasing the dose of topiramate. The lowest dose of topiramate causing palinopsia was 25 mg twice a day. More than half of our patients reported exacerbation of visual disturbance in early morning or late evening. Conclusions: Topiramate-induced palinopsia may be underdiagnosed because physicians do not inquire about such visual symptoms.

Original languageEnglish (US)
Pages (from-to)148-151
Number of pages4
JournalJournal of Neuro-Ophthalmology
Issue number2
StatePublished - Jun 30 2015

ASJC Scopus subject areas

  • Clinical Neurology
  • Ophthalmology


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