Tie Me Up, Tie Me Down: Inhibiting RNA Polymerase

Rui Sousa

Research output: Contribution to journalShort surveypeer-review

10 Scopus citations


Mechanistic understanding of antibiotic action can yield crucial insights that aid in the design of new antibiotics. In this issue, Mukhopadhyay et al. (2008) uncover the mechanism by which the antibiotic myxopyronin inhibits bacterial RNA polymerase, suggesting a new target region in RNA polymerase for inhibitor design.

Original languageEnglish (US)
Pages (from-to)205-207
Number of pages3
Issue number2
StatePublished - Oct 17 2008

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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