Thyrocalcitonin: Stimulation of secretion by pentagastrin

Cary W. Cooper, Wayne H. Schwesinger, Ahmed M. Mahgoub, David A. Ontjes

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Abstract

Administration of a small dose of pentagastrin, a synthetic pentapeptide containing the biologically active portion of the native hormone gastrin, results in a marked, rapid, transitory increase in thyrocalcitonin secretion in the pig. Gastrin or a related gastrointestinal peptide may be important in the physiological secretion of thyrocalcitonin, such as that which occurs when calcium salts are introduced into the gastrointestinal tract.

Original languageEnglish (US)
Pages (from-to)1238-1240
Number of pages3
JournalScience
Volume172
Issue number3989
DOIs
Publication statusPublished - Jan 1 1971

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Cooper, C. W., Schwesinger, W. H., Mahgoub, A. M., & Ontjes, D. A. (1971). Thyrocalcitonin: Stimulation of secretion by pentagastrin. Science, 172(3989), 1238-1240. https://doi.org/10.1126/science.172.3989.1238