Thromboxane in Ischemic Heart Disease

Robert Ira Lewy; Edwin W. Salzman; Michael Sobel; Allan B. Zelinger; Edgar C. Schick; Thomas J. Ryan; Andrzej Zalewski; Paul D. Hirsh; L. David Hillis; William B. Campbell; Brian G. Firth; James T. Willerson

doi:10.1056/NEJM198107093050219

Thromboxane in Ischemic Heart Disease

Robert Ira Lewy, Edwin W. Salzman, Michael Sobel, Allan B. Zelinger, Edgar C. Schick, Thomas J. Ryan, Andrzej Zalewski, Paul D. Hirsh, L. David Hillis, William B. Campbell, Brian G. Firth, James T. Willerson

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

Abstract

To the Editor: The report by Hirsh et al. in the March 19 issue,¹ in which increased levels of coronary-sinus thromboxane B₂ were demonstrated in patients with recent episodes of angina, supports previous experimental data showing increased thromboxane B₂ levels in coronary-sinus blood of patients with exercise-induced angina² and of patients with fixed obstructive coronary-artery disease in whom angina was induced by rapid atrial pacing.³ It is of broader potential importance that levels of thromboxane B₂ in peripheral blood have been shown by several investigators to rise acutely during chest pain in patients known to have coronary-artery. . .

Original language	English (US)
Pages (from-to)	106-107
Number of pages	2
Journal	New England Journal of Medicine
Volume	305
Issue number	2
DOIs	https://doi.org/10.1056/NEJM198107093050219
State	Published - Jul 9 1981
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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title = "Thromboxane in Ischemic Heart Disease",

abstract = "To the Editor: The report by Hirsh et al. in the March 19 issue,1 in which increased levels of coronary-sinus thromboxane B2 were demonstrated in patients with recent episodes of angina, supports previous experimental data showing increased thromboxane B2 levels in coronary-sinus blood of patients with exercise-induced angina2 and of patients with fixed obstructive coronary-artery disease in whom angina was induced by rapid atrial pacing.3 It is of broader potential importance that levels of thromboxane B2 in peripheral blood have been shown by several investigators to rise acutely during chest pain in patients known to have coronary-artery. . .",

author = "Lewy, {Robert Ira} and Salzman, {Edwin W.} and Michael Sobel and Zelinger, {Allan B.} and Schick, {Edgar C.} and Ryan, {Thomas J.} and Andrzej Zalewski and Hirsh, {Paul D.} and Hillis, {L. David} and Campbell, {William B.} and Firth, {Brian G.} and Willerson, {James T.}",

year = "1981",

month = jul,

day = "9",

doi = "10.1056/NEJM198107093050219",

language = "English (US)",

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pages = "106--107",

journal = "New England Journal of Medicine",

issn = "0028-4793",

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TY - JOUR

T1 - Thromboxane in Ischemic Heart Disease

AU - Lewy, Robert Ira

AU - Salzman, Edwin W.

AU - Sobel, Michael

AU - Zelinger, Allan B.

AU - Schick, Edgar C.

AU - Ryan, Thomas J.

AU - Zalewski, Andrzej

AU - Hirsh, Paul D.

AU - Hillis, L. David

AU - Campbell, William B.

AU - Firth, Brian G.

AU - Willerson, James T.

PY - 1981/7/9

Y1 - 1981/7/9

N2 - To the Editor: The report by Hirsh et al. in the March 19 issue,1 in which increased levels of coronary-sinus thromboxane B2 were demonstrated in patients with recent episodes of angina, supports previous experimental data showing increased thromboxane B2 levels in coronary-sinus blood of patients with exercise-induced angina2 and of patients with fixed obstructive coronary-artery disease in whom angina was induced by rapid atrial pacing.3 It is of broader potential importance that levels of thromboxane B2 in peripheral blood have been shown by several investigators to rise acutely during chest pain in patients known to have coronary-artery. . .

AB - To the Editor: The report by Hirsh et al. in the March 19 issue,1 in which increased levels of coronary-sinus thromboxane B2 were demonstrated in patients with recent episodes of angina, supports previous experimental data showing increased thromboxane B2 levels in coronary-sinus blood of patients with exercise-induced angina2 and of patients with fixed obstructive coronary-artery disease in whom angina was induced by rapid atrial pacing.3 It is of broader potential importance that levels of thromboxane B2 in peripheral blood have been shown by several investigators to rise acutely during chest pain in patients known to have coronary-artery. . .

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Thromboxane in Ischemic Heart Disease

Abstract

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