Therapeutic cytapheresis in chronic lymphocytic leukemia

G. E. Marti, T. Folks, D. L. Longo, H. Klein

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


The role of therapeutic reductive lymphapheresis in 59 patients with chronic lymphocytic leukemia (CLL) was reviewed. Reduction in lymphocytosis, lymphadenopathy and hepatosplenomegaly was noted in 50%–60% of the patients studied. In addition to mobilization of the lymphoid tumor load, 40% of the patients showed an improvement in their hemogram. Although apheresis‐induced anemia can occur, reported complications were minimal. These studies suggest that a majority of CLL patients might benefit from therapeutic lymphapheresis.

Original languageEnglish (US)
Pages (from-to)243-248
Number of pages6
JournalJournal of Clinical Apheresis
Issue number4
StatePublished - 1983
Externally publishedYes


  • CLL
  • lymphapheresis
  • therapeutic

ASJC Scopus subject areas

  • Hematology


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