Therapeutic cytapheresis in chronic lymphocytic leukemia

G. E. Marti, T. Folks, D. L. Longo, H. Klein

    Research output: Contribution to journalReview articlepeer-review

    4 Scopus citations

    Abstract

    The role of therapeutic reductive lymphapheresis in 59 patients with chronic lymphocytic leukemia (CLL) was reviewed. Reduction in lymphocytosis, lymphadenopathy and hepatosplenomegaly was noted in 50%–60% of the patients studied. In addition to mobilization of the lymphoid tumor load, 40% of the patients showed an improvement in their hemogram. Although apheresis‐induced anemia can occur, reported complications were minimal. These studies suggest that a majority of CLL patients might benefit from therapeutic lymphapheresis.

    Original languageEnglish (US)
    Pages (from-to)243-248
    Number of pages6
    JournalJournal of Clinical Apheresis
    Volume1
    Issue number4
    DOIs
    StatePublished - 1983

    Keywords

    • CLL
    • lymphapheresis
    • therapeutic

    ASJC Scopus subject areas

    • Hematology

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