Therapeutic cytapheresis in chronic lymphocytic leukemia

G. E. Marti; T. Folks; D. L. Longo; H. Klein

doi:10.1002/jca.2920010408

Therapeutic cytapheresis in chronic lymphocytic leukemia

G. E. Marti, T. Folks, D. L. Longo, H. Klein

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

The role of therapeutic reductive lymphapheresis in 59 patients with chronic lymphocytic leukemia (CLL) was reviewed. Reduction in lymphocytosis, lymphadenopathy and hepatosplenomegaly was noted in 50%–60% of the patients studied. In addition to mobilization of the lymphoid tumor load, 40% of the patients showed an improvement in their hemogram. Although apheresis‐induced anemia can occur, reported complications were minimal. These studies suggest that a majority of CLL patients might benefit from therapeutic lymphapheresis.

Original language	English (US)
Pages (from-to)	243-248
Number of pages	6
Journal	Journal of Clinical Apheresis
Volume	1
Issue number	4
DOIs	https://doi.org/10.1002/jca.2920010408
State	Published - 1983

Keywords

CLL
lymphapheresis
therapeutic

ASJC Scopus subject areas

Hematology

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abstract = "The role of therapeutic reductive lymphapheresis in 59 patients with chronic lymphocytic leukemia (CLL) was reviewed. Reduction in lymphocytosis, lymphadenopathy and hepatosplenomegaly was noted in 50%–60% of the patients studied. In addition to mobilization of the lymphoid tumor load, 40% of the patients showed an improvement in their hemogram. Although apheresis‐induced anemia can occur, reported complications were minimal. These studies suggest that a majority of CLL patients might benefit from therapeutic lymphapheresis.",

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AU - Marti, G. E.

AU - Folks, T.

AU - Longo, D. L.

AU - Klein, H.

PY - 1983

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N2 - The role of therapeutic reductive lymphapheresis in 59 patients with chronic lymphocytic leukemia (CLL) was reviewed. Reduction in lymphocytosis, lymphadenopathy and hepatosplenomegaly was noted in 50%–60% of the patients studied. In addition to mobilization of the lymphoid tumor load, 40% of the patients showed an improvement in their hemogram. Although apheresis‐induced anemia can occur, reported complications were minimal. These studies suggest that a majority of CLL patients might benefit from therapeutic lymphapheresis.

AB - The role of therapeutic reductive lymphapheresis in 59 patients with chronic lymphocytic leukemia (CLL) was reviewed. Reduction in lymphocytosis, lymphadenopathy and hepatosplenomegaly was noted in 50%–60% of the patients studied. In addition to mobilization of the lymphoid tumor load, 40% of the patients showed an improvement in their hemogram. Although apheresis‐induced anemia can occur, reported complications were minimal. These studies suggest that a majority of CLL patients might benefit from therapeutic lymphapheresis.

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KW - therapeutic

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