The Yale-Brown Obsessive Compulsive Scale: II. Validity

Wayne K. Goodman, Lawrence H. Price, Steven A. Rasmussen, Carolyn Mazure, Pedro Delgado, George R. Heninger, Dennis S. Charney

Research output: Contribution to journalArticlepeer-review

2240 Scopus citations

Abstract

The development design and reliability of the Yale-Brown Obsessive Compulsive Scale have been described elsewhere. We focused on the validity of the Yale-Brown Scale and its sensitivity to change. Convergent and discriminant validity were examined in baseline ratings from three cohorts of patients with obsessive-compulsive disorder (N = 81). The total Yale-Brown Scale score was significantly correlated with two of three independent measures of obsessive-compulsive disorder and weakly correlated with measures of depression and of anxiety in patients with obsessive-compulsive disorder with minimal secondary depressive symptoms. Results from a previously reported placebo-controlled trial of fluvoxamine in 42 patients with obsessive-compulsive disorder showed that the Yale-Brown Scale was sensitive to drug-induced changes and that reductions in Yale-Brown Scale scores specifically reflected improvement in obsessive-compulsive disorder symptoms. Together, these studies indicate that the 10-item Yale-Brown Scale is a reliable and valid instrument for assessing obsessive-compulsive disorder symptom severity and that it is suitable as an outcome measure in drug trials of obsessive-compulsive disorder.

Original languageEnglish (US)
Pages (from-to)1012-1016
Number of pages5
JournalArchives of General Psychiatry
Volume46
Issue number11
DOIs
StatePublished - Nov 1989

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health

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