The Vibrio Polar Flagellum: Structure and Regulation

Cameron J. Lloyd, Karl E. Klose

Research output: Contribution to journalArticlepeer-review


Here we discuss the structure and regulation of the Vibrio flagellum and its role in the virulence of pathogenic species. We will cover some of the novel insights into the structure of this nanomachine that have recently been enabled by cryoelectron tomography. We will also highlight the recent genetic studies that have increased our understanding in flagellar synthesis specifically at the bacterial cell pole, temporal regulation of flagellar genes, and how the flagellum enables directional motility through Run-Reverse-Flick cycles.

Original languageEnglish (US)
Pages (from-to)77-97
Number of pages21
JournalAdvances in experimental medicine and biology
StatePublished - 2023


  • Flagellar structure
  • Flagellar synthesis
  • Vibrio flagellum

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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