The use of the theory of planned behavior to predict medication adherence in schizophrenia

Alex Kopelowicz; Charles Wallace; Robert Paul Liberman; Fabian Aguirre; Roberto Zarate; Jim Mintz

doi:10.3371/CSRP.1.3.2

The use of the theory of planned behavior to predict medication adherence in schizophrenia

Alex Kopelowicz, Charles Wallace, Robert Paul Liberman, Fabian Aguirre, Roberto Zarate, Jim Mintz

Research output: Contribution to journal › Article

11 Scopus citations

Abstract

Objective: Inadequate adherence to antipsychotic medication regimens is common among patients with schizophrenia. This study evaluated the psychometric properties of a new instrument designed to identify the factors associated with poor adherence to antipsychotic medications in this population. Methods: Spanish-speaking, Mexican-American adult patients with schizophrenia (N=155) were administered the newly developed Theory of Planned Behavior (TPB) Inventory, as well as the Rating of Medication Influences (ROMI) scale and the Treatment Compliance Interview (TCI). The latter two instruments are commonly used and well validated for the assessment of medication adherence among patients with schizophrenia. Results: The TPB Inventory demonstrated high internal consistency, excellent test-retest reliability and good concurrent validity with the ROMI. In addition, the TPB Inventory showed good predictive validity with patients' intentions to take medication as prescribed and actual adherence behavior. Conclusions: The TPB Inventory is a reliable and valid instrument that can be used to assess the factors associated with medication nonadherence. Better understanding of these factors can guide clinicians in their efforts to improve medication adherence among patients with schizophrenia.

Original language	English (US)
Pages (from-to)	227-242
Number of pages	16
Journal	Clinical Schizophrenia and Related Psychoses
Volume	1
Issue number	3
DOIs	https://doi.org/10.3371/CSRP.1.3.2
State	Published - Dec 1 2007
Externally published	Yes

Keywords

Antipsychotic Medications
Hispanic
Medication Adherence
Schizophrenia
Theory of Planned Behavior

ASJC Scopus subject areas

Psychiatry and Mental health

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Kopelowicz, A., Wallace, C., Liberman, R. P., Aguirre, F., Zarate, R., & Mintz, J. (2007). The use of the theory of planned behavior to predict medication adherence in schizophrenia. Clinical Schizophrenia and Related Psychoses, 1(3), 227-242. https://doi.org/10.3371/CSRP.1.3.2

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AU - Mintz, Jim

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N2 - Objective: Inadequate adherence to antipsychotic medication regimens is common among patients with schizophrenia. This study evaluated the psychometric properties of a new instrument designed to identify the factors associated with poor adherence to antipsychotic medications in this population. Methods: Spanish-speaking, Mexican-American adult patients with schizophrenia (N=155) were administered the newly developed Theory of Planned Behavior (TPB) Inventory, as well as the Rating of Medication Influences (ROMI) scale and the Treatment Compliance Interview (TCI). The latter two instruments are commonly used and well validated for the assessment of medication adherence among patients with schizophrenia. Results: The TPB Inventory demonstrated high internal consistency, excellent test-retest reliability and good concurrent validity with the ROMI. In addition, the TPB Inventory showed good predictive validity with patients' intentions to take medication as prescribed and actual adherence behavior. Conclusions: The TPB Inventory is a reliable and valid instrument that can be used to assess the factors associated with medication nonadherence. Better understanding of these factors can guide clinicians in their efforts to improve medication adherence among patients with schizophrenia.

AB - Objective: Inadequate adherence to antipsychotic medication regimens is common among patients with schizophrenia. This study evaluated the psychometric properties of a new instrument designed to identify the factors associated with poor adherence to antipsychotic medications in this population. Methods: Spanish-speaking, Mexican-American adult patients with schizophrenia (N=155) were administered the newly developed Theory of Planned Behavior (TPB) Inventory, as well as the Rating of Medication Influences (ROMI) scale and the Treatment Compliance Interview (TCI). The latter two instruments are commonly used and well validated for the assessment of medication adherence among patients with schizophrenia. Results: The TPB Inventory demonstrated high internal consistency, excellent test-retest reliability and good concurrent validity with the ROMI. In addition, the TPB Inventory showed good predictive validity with patients' intentions to take medication as prescribed and actual adherence behavior. Conclusions: The TPB Inventory is a reliable and valid instrument that can be used to assess the factors associated with medication nonadherence. Better understanding of these factors can guide clinicians in their efforts to improve medication adherence among patients with schizophrenia.

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