The use of fine needle aspiration cytology for the distinction of pancreatic mucinous neoplasia

Edward B. Stelow, Vanessa M. Shami, Todd E. Abbott, Michelle Kahaleh, Reid B. Adams, Todd W. Bauer, Steven M. Debol, James M. Abraham, Shawn Mallery, Maria Luisa Policarpio-Nicolas

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Cytology frequently has some role in preoperatively distinguishing pancreatic mucus-producing neoplasia (intraductal papillary mucinous neoplasms [IPMNs] and mucinous cystic neoplasms [MCNs]) from other pancreatic cysts. We evaluated all cytologic specimens at our institutions from resected pancreatic cystic lesions for lesional extracellular and cellular material. Lesional extracellular material was identified in 32 of 38 of the cytologic samples from cystic pancreatic mucus-producing neoplasms (28 of 31 IPMNs and 4 of 7 MCNs). Lesional cellular material was seen in 22 of 38 cases (17 of 31 IPMNs and 5 of 7 MCNs). Lesional material was more commonly identified in higher grade and invasive lesions. Lesional extracellular material was seen in 3 of 14 samples of other pancreatic cysts, and lesional cellular material was seen in 6 of 14 cases.

Original languageEnglish (US)
Pages (from-to)67-74
Number of pages8
JournalAmerican journal of clinical pathology
Volume129
Issue number1
DOIs
StatePublished - Jan 2008

Keywords

  • Endoscopic ultrasound
  • Fine-needle aspiration
  • Intraductal papillary mucinous neoplasm
  • Lymphoepithelial cyst
  • Mucinous cystic neoplasm
  • Pancreas
  • Pancreatic endocrine tumor
  • Pseudocyst

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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