The use of cefotaxime in the treatment of gram-positive pneumonias

S. G. Jenkinson

doi:10.1007/BF01644211

The use of cefotaxime in the treatment of gram-positive pneumonias

S. G. Jenkinson

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A single-blind, prospective, randomized comparison of cefotaxime and cefazolin was conducted in 356 patients with gram-positive pneumonias. Clinical cure was achieved in 95.9% of patients receiving cefotaxime and 94% of patients receiving cefazolin. In a sub-group of patients with Staphylococcus aureus pneumonia, clinical cure was obtained in 31 of 37 patients treated with cefotaxime and all of six patients treated with cefazolin. Cefotaxime was well tolerated, safe, and efficacious. These data support the use of cefotaxime as an initial single antibiotic in treating patients with gram-positive pneumonias due to susceptible organisms.

Original language	English (US)
Pages (from-to)	S14-S17
Journal	Infection
Volume	13
Issue number	1 Supplement
DOIs	https://doi.org/10.1007/BF01644211
State	Published - Jan 1985
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1007/BF01644211

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abstract = "A single-blind, prospective, randomized comparison of cefotaxime and cefazolin was conducted in 356 patients with gram-positive pneumonias. Clinical cure was achieved in 95.9% of patients receiving cefotaxime and 94% of patients receiving cefazolin. In a sub-group of patients with Staphylococcus aureus pneumonia, clinical cure was obtained in 31 of 37 patients treated with cefotaxime and all of six patients treated with cefazolin. Cefotaxime was well tolerated, safe, and efficacious. These data support the use of cefotaxime as an initial single antibiotic in treating patients with gram-positive pneumonias due to susceptible organisms.",

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AB - A single-blind, prospective, randomized comparison of cefotaxime and cefazolin was conducted in 356 patients with gram-positive pneumonias. Clinical cure was achieved in 95.9% of patients receiving cefotaxime and 94% of patients receiving cefazolin. In a sub-group of patients with Staphylococcus aureus pneumonia, clinical cure was obtained in 31 of 37 patients treated with cefotaxime and all of six patients treated with cefazolin. Cefotaxime was well tolerated, safe, and efficacious. These data support the use of cefotaxime as an initial single antibiotic in treating patients with gram-positive pneumonias due to susceptible organisms.

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ER -

The use of cefotaxime in the treatment of gram-positive pneumonias

Abstract

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