The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells

Biochemistry, Genetics and Molecular Biology

• P53 100%
• Nutlin 61%
• Apoptosis 28%
• Mitochondrion 9%
• Transcription 9%
• Nested Gene 4%
• Wild Type 4%
• Ubiquitin Ligase 4%
• Cell Death 4%
• Growth 4%
• Cytochrome C 4%
• Species 4%
• Aptitude 4%
• thought 4%

Pharmacology, Toxicology and Pharmaceutical Science

• Protein P53 100%
• Nutlin 61%
• Apoptosis 28%
• Neoplasm 19%
• Cytochrome C 4%
• Growth Disorder 4%
• Malignant Neoplasm 4%
• Ubiquitin Protein Ligase E3 4%
• Cell Death 4%
• Amatoxin 4%

Chemistry

• Nutlin 61%
• Apoptotic 9%
• Chemical Activation 9%
• Inhibitor 9%
• % Inhibition 4%
• Cell Death 4%
• Cytochrome C 4%
• Genotoxic 4%
• Pool 4%
• Block Like Crystal 4%