Abstract
(matrix presented) A new alkyl-substituted nonenolide, microcarpalide 1, has been isolated from fermentation broths of an unidentified endophytic fungus. Microcarpalide is weakly cytotoxic to mammalian cells and acts as a microfilament disrupting agent. The structure of 1 was elucidated by application of spectroscopic methods. The absolute configuration was determined by the exciton chirality method.
Original language | English (US) |
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Pages (from-to) | 3479-3481 |
Number of pages | 3 |
Journal | Organic Letters |
Volume | 3 |
Issue number | 22 |
DOIs | |
State | Published - Nov 1 2001 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry