The specificity of antibodies elicited by poly(Dg) poly(dc)

Eileen M. Lafer, B. David Stollar

Research output: Contribution to journalArticle

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Abstract

Antibodies have been raised to the synthetic DNA polymer poly(dG) poly(dC). These antibodies have the ability to distinguish this right-handed polymer from natural mixed sequence DNA, as well as from other right- and left-handed synthetic DNA polymers. They show reduced but measurable binding to synthetic polymers which contain various combinations of guanine and cytosine polynucleotides suggesting that both helical shape and sequence are recognized by this antiserum.

Original languageEnglish (US)
Pages (from-to)487-494
Number of pages8
JournalJournal of Biomolecular Structure and Dynamics
Volume2
Issue number3
DOIs
StatePublished - Dec 1984

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ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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