The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer

Ronald L. Stephens; James R. Eltringham; Charles A. Coltman; James Neidhart; James Mullins; Jess Frank

doi:10.1016/0360-3016(83)90357-7

The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer

Ronald L. Stephens, James R. Eltringham, Charles A. Coltman, James Neidhart, James Mullins, Jess Frank

Research output: Contribution to journal › Article › peer-review

Abstract

During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.

Original language	English (US)
Pages (from-to)	1885-1890
Number of pages	6
Journal	International journal of radiation oncology, biology, physics
Volume	9
Issue number	12
DOIs	https://doi.org/10.1016/0360-3016(83)90357-7
State	Published - Dec 1983
Externally published	Yes

Keywords

Adjuvant treatment
Testis cancer

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

Access to Document

10.1016/0360-3016(83)90357-7

Cite this

@article{c4a881ba27e845bebec6b28d15123298,

title = "The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer",

abstract = "During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.",

keywords = "Adjuvant treatment, Testis cancer",

author = "Stephens, {Ronald L.} and Eltringham, {James R.} and Coltman, {Charles A.} and James Neidhart and James Mullins and Jess Frank",

note = "Funding Information: {\textquoteleft}University of Texas Health Sciences Center at San Antonio. 40hio State University Hospital. {\textquoteleft}Wilford Hall Medical Center. %outhwest Oncology Group Biostatistical Center Houston, TX. This investigation was supported in part by the following PHS grant numbers awarded by the National Cancer Institute, DHHS: CA-l 2644, CA-I 3238, CA-22433, CA-04920, CA-",

year = "1983",

month = dec,

doi = "10.1016/0360-3016(83)90357-7",

language = "English (US)",

volume = "9",

pages = "1885--1890",

journal = "International Journal of Radiation Oncology Biology Physics",

issn = "0360-3016",

publisher = "Elsevier Inc.",

number = "12",

}

TY - JOUR

T1 - The southwest oncology group experience

T2 - adjuvant therapy for stage IB and II non-seminomatous testicular cancer

AU - Stephens, Ronald L.

AU - Eltringham, James R.

AU - Coltman, Charles A.

AU - Neidhart, James

AU - Mullins, James

AU - Frank, Jess

N1 - Funding Information: ‘University of Texas Health Sciences Center at San Antonio. 40hio State University Hospital. ‘Wilford Hall Medical Center. %outhwest Oncology Group Biostatistical Center Houston, TX. This investigation was supported in part by the following PHS grant numbers awarded by the National Cancer Institute, DHHS: CA-l 2644, CA-I 3238, CA-22433, CA-04920, CA-

PY - 1983/12

Y1 - 1983/12

N2 - During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.

AB - During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.

KW - Adjuvant treatment

KW - Testis cancer

UR - http://www.scopus.com/inward/record.url?scp=0021015776&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021015776&partnerID=8YFLogxK

U2 - 10.1016/0360-3016(83)90357-7

DO - 10.1016/0360-3016(83)90357-7

M3 - Article

C2 - 6198313

AN - SCOPUS:0021015776

VL - 9

SP - 1885

EP - 1890

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

SN - 0360-3016

IS - 12

ER -

The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this