The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer

Ronald L. Stephens, James R. Eltringham, Charles A. Coltman, James Neidhart, James Mullins, Jess Frank

Research output: Contribution to journalArticlepeer-review

Abstract

During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.

Original languageEnglish (US)
Pages (from-to)1885-1890
Number of pages6
JournalInternational journal of radiation oncology, biology, physics
Volume9
Issue number12
DOIs
StatePublished - Dec 1983
Externally publishedYes

Keywords

  • Adjuvant treatment
  • Testis cancer

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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