The role of natural occurring infections in experimental studies in non-human primates

Natalia Schlabritz-Loutsevitch, Edward J. Dick, Gene B. Hubbard

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Non-human primates (NHP) have been an indispensable part of experimental medicine for centuries. Baboons (Papio spp.) have been extensively used in reproductive research and are a well characterized model of premature labor, endometriosis and pregnancy perturbations. However, the role of naturally occurring infectious agents in reproductive research using these non-human primate species has received less attention. Microbial participation is essential for host functions such as defense, metabolism, and reproduction. The possible role of turbulences in the placental microbial communities has been linked to preterm deliveries [1]. Changes in the fecal microbiome have been recently recognized as an essential part of both inflammation [2] and pregnancy [3]. This chapter will describe the most common infectious pathologies in baboons and their influence on reproductive research.

Original languageEnglish (US)
Title of host publicationMonkeys: Brain Development, Social & Hormonal Mechanisms and Zoonotic Diseases
PublisherNova Science Publishers, Inc.
Pages149-162
Number of pages14
ISBN (Electronic)9781631178528
ISBN (Print)9781631178511
StatePublished - Apr 1 2014

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • veterinary(all)

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    Schlabritz-Loutsevitch, N., Dick, E. J., & Hubbard, G. B. (2014). The role of natural occurring infections in experimental studies in non-human primates. In Monkeys: Brain Development, Social & Hormonal Mechanisms and Zoonotic Diseases (pp. 149-162). Nova Science Publishers, Inc..