TY - JOUR
T1 - The risk of alcohol intake in men and women
T2 - All may not be equal
AU - Schenker, Steven
AU - Speeg, K. Vincent
PY - 1990/1/11
Y1 - 1990/1/11
N2 - The concentration of alcohol in the blood and other tissues is the result of its intake route, usually oral, its distribution, and its rate of elimination. Although the enzymes primarily responsible for alcohol metabolism, the alcohol dehydrogenases, are present in many tissues, the liver has traditionally been considered the principal site of alcohol metabolism. In this issue of the Journal, Frezza et al.1 report that alcohol dehydrogenase in the gastric mucosa may contribute substantially to alcohol metabolism, that this effect varies with sex, and that the gastric metabolism of alcohol is decreased in women and men with chronic alcoholism.
AB - The concentration of alcohol in the blood and other tissues is the result of its intake route, usually oral, its distribution, and its rate of elimination. Although the enzymes primarily responsible for alcohol metabolism, the alcohol dehydrogenases, are present in many tissues, the liver has traditionally been considered the principal site of alcohol metabolism. In this issue of the Journal, Frezza et al.1 report that alcohol dehydrogenase in the gastric mucosa may contribute substantially to alcohol metabolism, that this effect varies with sex, and that the gastric metabolism of alcohol is decreased in women and men with chronic alcoholism.
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U2 - 10.1056/NEJM199001113220211
DO - 10.1056/NEJM199001113220211
M3 - Editorial
C2 - 2403653
AN - SCOPUS:0025023497
VL - 322
SP - 127
EP - 129
JO - New England Journal of Medicine
JF - New England Journal of Medicine
SN - 0028-4793
IS - 2
ER -