The risk and outcomes of pneumonia in patients on inhaled corticosteroids

Oriol Sibila; Natalia Soto-Gomez; Marcos I. Restrepo

doi:10.1016/j.pupt.2015.04.001

The risk and outcomes of pneumonia in patients on inhaled corticosteroids

Oriol Sibila, Natalia Soto-Gomez, Marcos I. Restrepo

Department of Medicine

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Corticosteroids are frequently prescribed anti-inflammatory medications. Inhaled corticosteroids (ICS) are indicated for Chronic Obstructive Pulmonary Disease (COPD) and asthma. ICS are associated with a decrease in exacerbations and improved quality of life in COPD, however multiple studies have linked the chronic use of ICSs with an increased risk of developing pneumonia, though the effect on mortality is unclear. We review the association of ICS with the risk of pneumonia and the implications on clinical outcomes.

Original language	English (US)
Pages (from-to)	130-136
Number of pages	7
Journal	Pulmonary Pharmacology and Therapeutics
Volume	32
DOIs	https://doi.org/10.1016/j.pupt.2015.04.001
State	Published - Jun 1 2015

Keywords

Chronic obstructive pulmonary disease
Inhaled corticosteroids
Pneumonia

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Biochemistry, medical
Pharmacology (medical)

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10.1016/j.pupt.2015.04.001

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abstract = "Corticosteroids are frequently prescribed anti-inflammatory medications. Inhaled corticosteroids (ICS) are indicated for Chronic Obstructive Pulmonary Disease (COPD) and asthma. ICS are associated with a decrease in exacerbations and improved quality of life in COPD, however multiple studies have linked the chronic use of ICSs with an increased risk of developing pneumonia, though the effect on mortality is unclear. We review the association of ICS with the risk of pneumonia and the implications on clinical outcomes.",

keywords = "Chronic obstructive pulmonary disease, Inhaled corticosteroids, Pneumonia",

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AU - Restrepo, Marcos I.

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AB - Corticosteroids are frequently prescribed anti-inflammatory medications. Inhaled corticosteroids (ICS) are indicated for Chronic Obstructive Pulmonary Disease (COPD) and asthma. ICS are associated with a decrease in exacerbations and improved quality of life in COPD, however multiple studies have linked the chronic use of ICSs with an increased risk of developing pneumonia, though the effect on mortality is unclear. We review the association of ICS with the risk of pneumonia and the implications on clinical outcomes.

KW - Chronic obstructive pulmonary disease

KW - Inhaled corticosteroids

KW - Pneumonia

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ER -

The risk and outcomes of pneumonia in patients on inhaled corticosteroids

Abstract

Keywords

ASJC Scopus subject areas

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