The relentless effects of the aging process on protein turnover

Walter F. Ward

doi:10.1023/A:1010076818119

The relentless effects of the aging process on protein turnover

Walter F. Ward

Barshop Institute

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Protein turnover encompasses the processes of protein synthesis and protein degradation. Because of the essential structural and catalytic roles that proteins play in the cell, there has been a long-standing interest in the effects of aging on protein turnover. The purpose of this review is to incorporate relevant data published since the area was previously reviewed and to provide an update on the status of research with particular attention to the pathways of protein degradation.

Original language	English (US)
Pages (from-to)	195-199
Number of pages	5
Journal	Biogerontology
Volume	1
Issue number	3
DOIs	https://doi.org/10.1023/A:1010076818119
State	Published - Jan 1 2000

Keywords

Aging
Lysosome
Proteasome
Protein degradation
Protein synthesis
Protein turnover

ASJC Scopus subject areas

Aging
Gerontology
Geriatrics and Gerontology

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AB - Protein turnover encompasses the processes of protein synthesis and protein degradation. Because of the essential structural and catalytic roles that proteins play in the cell, there has been a long-standing interest in the effects of aging on protein turnover. The purpose of this review is to incorporate relevant data published since the area was previously reviewed and to provide an update on the status of research with particular attention to the pathways of protein degradation.

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The relentless effects of the aging process on protein turnover

Abstract

Keywords

ASJC Scopus subject areas

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