The prevalence, risk factors and clinical correlates of obesity in Chinese patients with schizophrenia

Qiongzhen Li, Xiangdong Du, Yingyang Zhang, Guangzhong Yin, Guangya Zhang, Consuelo Walss-Bass, João Quevedo, Jair C. Soares, Haishen Xia, Xiaosi Li, Yingjun Zheng, Yuping Ning, Xiang Yang Zhang

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Obesity is a common comorbidity in schizophrenia. Few studies have addressed obesity in Chinese schizophrenia patients. The aims of this current study were to evaluate the prevalence, risk factors and clinical correlates of obesity in Chinese patients with schizophrenia. A total of 206 patients were recruited from a hospital in Beijing. Their clinical and anthropometric data together with plasma glucose and lipid parameters were collected. Positive and Negative Syndrome Scale (PANSS) was rated for all patients. Overall, 43 (20.9%) patients were obese and 67 (32.5%) were overweight. The obese patients had significantly higher glucose levels, triglyceride levels than non-obese patients. Females and patients with type 2 diabetes mellitus had increased risk for obesity. Correlation analysis showed that BMI was associated with sex, education levels, negative symptoms, total PANSS score, triglyceride levels and type 2 diabetes mellitus. Further stepwise regression analysis showed that sex, type 2 diabetes, education level, triglyceride and amount of smoking/day were significant predictors for obesity. Our study showed that the prevalence of obesity in Chinese patients with schizophrenia is higher than that in the general population. Some demographic and clinical variables are risk factors for obesity in schizophrenia.

Original languageEnglish (US)
Pages (from-to)131-136
Number of pages6
JournalPsychiatry Research
Volume251
DOIs
StatePublished - May 1 2017
Externally publishedYes

Keywords

  • BMI
  • Chinese
  • Obesity
  • PANSS
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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