The PHACES syndrome: Multiple episodes of reproliferation of subglottic hemangioma

Randall W. Holdgraf, Melissa Kress

Research output: Contribution to journalArticlepeer-review

Abstract

Subglottic hemangioma is a potentially life-threatening manifestation of the PHACES syndrome. The disease process has been treated with corticosteroids, oral chemotherapeutic agents, endoscopic airway interventions, tracheostomy, and even laryngotracheal reconstruction. Oral propranolol has emerged as an effective therapy and in many cases has led to complete regression of hemangioma during the proliferative phase. There have been several reports of patients showing signs of reproliferation after discontinuing propranolol therapy. This article illustrates a patient who has had multiple episodes of reproliferation of subglottic hemangioma after weaning from propranolol therapy.

Original languageEnglish (US)
Pages (from-to)194-196
Number of pages3
JournalBaylor University Medical Center Proceedings
Volume31
Issue number2
DOIs
StatePublished - Apr 3 2018

Keywords

  • PHACES syndrome
  • propranolol
  • subglottic hemangioma

ASJC Scopus subject areas

  • Medicine(all)

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