The paradoxical effect on pneumonia of chronic inhaled corticosteroids

Oriol Sibila, Antonio Anzueto, Marcos I. Restrepo

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Several studies have shown that the risk of pneumonia is increased in patients with chronic obstructive pulmonary disease (COPD) who are receiving chronic inhaled corticosteroids (ICS). The impact of ICS on pneumonia prognosis is controversial. Recent studies have shown that COPD patients with prior ICS use have less mortality after developing CAP as compared with patients with COPD without prior ICS use. This review discusses the association of ICS and the risk of CAP and its association with clinical outcomes in patients with COPD and pneumonia.

Original languageEnglish (US)
Pages (from-to)6-10
Number of pages5
JournalClinical Pulmonary Medicine
Volume20
Issue number1
DOIs
StatePublished - Jan 2013

Keywords

  • COPD
  • inhaled steroids
  • pneumonia

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

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