The paradoxical effect on pneumonia of chronic inhaled corticosteroids

Oriol Sibila; Antonio Anzueto; Marcos I. Restrepo

doi:10.1097/CPM.0b013e31827a2a60

The paradoxical effect on pneumonia of chronic inhaled corticosteroids

Oriol Sibila, Antonio Anzueto, Marcos I. Restrepo

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Several studies have shown that the risk of pneumonia is increased in patients with chronic obstructive pulmonary disease (COPD) who are receiving chronic inhaled corticosteroids (ICS). The impact of ICS on pneumonia prognosis is controversial. Recent studies have shown that COPD patients with prior ICS use have less mortality after developing CAP as compared with patients with COPD without prior ICS use. This review discusses the association of ICS and the risk of CAP and its association with clinical outcomes in patients with COPD and pneumonia.

Original language	English (US)
Pages (from-to)	6-10
Number of pages	5
Journal	Clinical Pulmonary Medicine
Volume	20
Issue number	1
DOIs	https://doi.org/10.1097/CPM.0b013e31827a2a60
State	Published - Jan 2013

Keywords

COPD
inhaled steroids
pneumonia

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

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10.1097/CPM.0b013e31827a2a60

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abstract = "Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Several studies have shown that the risk of pneumonia is increased in patients with chronic obstructive pulmonary disease (COPD) who are receiving chronic inhaled corticosteroids (ICS). The impact of ICS on pneumonia prognosis is controversial. Recent studies have shown that COPD patients with prior ICS use have less mortality after developing CAP as compared with patients with COPD without prior ICS use. This review discusses the association of ICS and the risk of CAP and its association with clinical outcomes in patients with COPD and pneumonia.",

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AU - Restrepo, Marcos I.

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N2 - Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Several studies have shown that the risk of pneumonia is increased in patients with chronic obstructive pulmonary disease (COPD) who are receiving chronic inhaled corticosteroids (ICS). The impact of ICS on pneumonia prognosis is controversial. Recent studies have shown that COPD patients with prior ICS use have less mortality after developing CAP as compared with patients with COPD without prior ICS use. This review discusses the association of ICS and the risk of CAP and its association with clinical outcomes in patients with COPD and pneumonia.

AB - Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Several studies have shown that the risk of pneumonia is increased in patients with chronic obstructive pulmonary disease (COPD) who are receiving chronic inhaled corticosteroids (ICS). The impact of ICS on pneumonia prognosis is controversial. Recent studies have shown that COPD patients with prior ICS use have less mortality after developing CAP as compared with patients with COPD without prior ICS use. This review discusses the association of ICS and the risk of CAP and its association with clinical outcomes in patients with COPD and pneumonia.

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KW - pneumonia

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The paradoxical effect on pneumonia of chronic inhaled corticosteroids

Abstract

Keywords

ASJC Scopus subject areas

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