The Natural Course of Pancreatic Cysts in Inflammatory Bowel Disease: Results of a Long-term Follow-up

Mohannad Abou Saleh, Motasem Alkhayyat, Alaa Habash, Ashraf Almomani, Farhan Qayyum, Woan Kim, James Bena, Charles Martin, Miguel Regueiro, Florian Rieder, Carlos Roberto Simons-Linares, Prabhleen Chahal

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives The natural course of pancreatic cysts in inflammatory bowel disease (IBD) is unknown. We aim to describe the natural course of pancreatic cysts in IBD and evaluate long-term outcomes. Methods A database of patients with abdominal imaging diagnosis of pancreatic cysts (2008-2019) was reviewed. Patients with IBD and pancreatic cysts (study group) and pancreatic cysts without IBD (controls) were selected. Outcomes were measured at 1, 3, 5, and 10 years. Several logistic regression models were used for analysis. Results Of the 1789 patients evaluated, 1690 had pancreatic cysts without IBD, and 78 had IBD and pancreatic cysts. Majority of cysts were intraductal papillary mucinous neoplasms. Patients with IBD and pancreatic cysts were more likely to be diagnosed with pancreatic cysts at a younger age (P < 0.001) and were more likely to undergo surgical intervention at a younger age (P < 0.001). Conclusions This is the first study to evaluate the natural course of pancreatic cysts in IBD patients. Patients with IBD were more likely to have pancreatic cysts detected at a younger age. Despite the early presentation, there were no differences in long-term outcomes. Patients with IBD with pancreatic cysts should be managed similarly to those without IBD.

Original languageEnglish (US)
Pages (from-to)814-820
Number of pages7
JournalPancreas
Volume51
Issue number7
DOIs
StatePublished - Aug 1 2022
Externally publishedYes

Keywords

  • Crohn disease
  • cystic
  • lesions
  • neoplasm
  • pancreas
  • ulcerative colitis

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Fingerprint

Dive into the research topics of 'The Natural Course of Pancreatic Cysts in Inflammatory Bowel Disease: Results of a Long-term Follow-up'. Together they form a unique fingerprint.

Cite this