The mouse as an investigational model for preterm labor

B. T. Oshiro, R. Silver, D. J. Dudley, M. D. Mitchell, D. Ware Branch

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

Preterm labor continues to be a leading cause of perinatal morbidity and mortality. In many cases the etiology of preterm labor is unknown. However, much interest has been generated surrounding the infectious causes of preterm labor. Because data suggest that preterm labor is preceded by a cascade of complex events, in vivo observations in humans and in vitro experiments using human tissue may not be sufficient to answer questions regarding its etiology. The murine model holds significant promise in delineating the chronology and specifics regarding the events precipitating preterm labor.

Original languageEnglish (US)
Pages (from-to)240-245
Number of pages6
JournalSeminars in Reproductive Endocrinology
Volume12
Issue number4
DOIs
StatePublished - 1994
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Reproductive Medicine
  • Endocrinology

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