The mortality of neonatal herpes simplex virus infection

Eduardo Lopez-Medina; Joseph B. Cantey; Pablo J. Sánchez

doi:10.1016/j.jpeds.2015.03.004

The mortality of neonatal herpes simplex virus infection

Eduardo Lopez-Medina
, Joseph B. Cantey
, Pablo J. Sánchez

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26% case-fatality rate. Fatal disease developed at ≤48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.

Original language	English (US)
Pages (from-to)	1529-1532.e1
Journal	Journal of Pediatrics
Volume	166
Issue number	6
DOIs	https://doi.org/10.1016/j.jpeds.2015.03.004
State	Published - Jun 1 2015
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/j.jpeds.2015.03.004

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title = "The mortality of neonatal herpes simplex virus infection",

abstract = "This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26\% case-fatality rate. Fatal disease developed at ≤48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.",

author = "Eduardo Lopez-Medina and Cantey, \{Joseph B.\} and S{\'a}nchez, \{Pablo J.\}",

year = "2015",

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AU - Cantey, Joseph B.

AU - Sánchez, Pablo J.

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N2 - This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26% case-fatality rate. Fatal disease developed at ≤48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.

AB - This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26% case-fatality rate. Fatal disease developed at ≤48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.

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UR - https://www.scopus.com/pages/publications/84930182854#tab=citedBy

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M3 - Article

C2 - 25868428

AN - SCOPUS:84930182854

SN - 0022-3476

VL - 166

SP - 1529-1532.e1

JO - Journal of Pediatrics

JF - Journal of Pediatrics

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ER -

The mortality of neonatal herpes simplex virus infection

Abstract

ASJC Scopus subject areas

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