TY - JOUR
T1 - The mortality of neonatal herpes simplex virus infection
AU - Lopez-Medina, Eduardo
AU - Cantey, Joseph B.
AU - Sánchez, Pablo J.
N1 - Publisher Copyright:
Copyright © 2015 Elsevier Inc. All rights reserved.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26% case-fatality rate. Fatal disease developed at ≤48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.
AB - This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26% case-fatality rate. Fatal disease developed at ≤48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.
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U2 - 10.1016/j.jpeds.2015.03.004
DO - 10.1016/j.jpeds.2015.03.004
M3 - Article
C2 - 25868428
AN - SCOPUS:84930182854
SN - 0022-3476
VL - 166
SP - 1529-1532.e1
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 6
ER -